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Bio-Fires – An Eco-Friendly Alternative to Real Fires Biofires provide a warm, comfortable form of warmth with no harmful gasses or soot. They are easy to install as an electrical fire. The BARDA contract will support the development of the BioFire emerging CoV panel, a nucleic-acid amplifying test that can be used in conjunction with BioFire filmArray Systems for detection of human acoronaviruses using nasopharyngeal or swabs and saliva samples. Eco-friendly A bioethanol fire is a great alternative to wood or gas fires. The fuel is created using plant by-products, and the natural process converts sugars into alcohol. It is a better option than other fireplaces since it does not emit harmful emissions, and has lower carbon footprint. Bioethanol is also a more secure alternative to other types of fires since it doesn't create smoke or soot. It does not require a flue, and can be used in the garden or at home. A multi-drug resistant (MDR) bacteria is one of the most serious health threats today. New testing methods can detect MDR bacteria early and help prevent any further complications. BioFire FilmArray is one such test. This test employs an approach based on symptoms to identify the most common pathogens that cause sepsis. The results are accessible within an hour, so doctors can start treatment immediately. The Molecular PCR process amplifies DNA and RNA molecules to millions or billions of copies. This makes it possible to test small amounts of body fluid or tissue to determine the presence of specific genetic sequences. It is a useful tool for laboratory professionals, and it can assist them in diagnosing serious illnesses in an efficient and cost-effective way. The BioFire film array PCR system is a revolutionary tool for infectious diseases diagnosis. It can be used in various environments, including hospitals and laboratories. In the case of respiratory tests, a simple swab can be wiped over your nose and sent to the lab for analysis. BioFire's system offers a quick turnaround time, allowing clinicians to act quickly. This means that patients will experience better outcomes and will spend less time waiting for the results. The Chanouf Farm Biofire company has developed an agroforestry recycling unit which makes use of olive and pear waste to make organic charcoal and biomass power. The resulting products are sold to the general public as a green alternative to traditional charcoal briquettes made of coal and wood. Additionally the bio-waste products can be used to fuel a Kachelofen fireplace that provides radiant heat that is greener than electric and gas fires. Clean burning With a bio-fire you don't just save energy, but also help the environment. This is because the burning of bioethanol does not produce harmful gases such as carbon dioxide. It releases only water vapour and heat. This makes it a safer and cleaner alternative for indoor use. Ethanol can be produced through the fermentation of sugars in plants. It is a renewable source of fuel. It can be produced quickly and won't run out as fossil fuels like oil and coal. The use of bioethanol can also help reduce dependence on imports from foreign countries and reduces the risks of supply shortages. The bio-fires can be erected easily, and can be placed in existing fireplace openings, or as standalone units. They are a viable alternative to wood and gas fires. They are also an excellent choice for offices and homes without a chimney or flue. When a bio-fire is ignited, a special media is built into the burner that absorbs the liquid ethanol fuel while making it ready for combustion. The ethanol fuel burns in the flames, and the smoke are released into the air through the vent. The flames appear more natural and gives an amazing beauty that cannot be replicated using gas or real wood fires. Another big advantage of bio-fires is that they don't require a flue or vent to replenish the oxygen consumed during combustion. They also don't create carbon monoxide which must be vented into the air in gas fires with open fronts. The BioFire Respiratory Panel employs multiplex technology that simultaneously tests for 19 respiratory pathogens in about an hour. This enables doctors to identify and eliminate respiratory diseases much faster than they can through standard tests that require patient visits. Both patients as well as the health system gain from this. Safe indoors Bio-fires are far safer to use indoors compared to real fires because they release no smoke or ash, nor carcinogenic fumes. They don't release carbon monoxide that can be harmful if inhaled. However the bio-ethanol fuel is flammable and you must be cautious when handling your burner and refuelling it. It should be replenished only after the burner has been switched off and the fire is cool, and any spills need to be cleaned immediately. The company's diagnostic FilmArray system – BioFire Torch and BioFire 2.0—are user-friendly and able to run eight different diagnostic panels approved by the US Food and Drug Administration as well as three additional panels approved for emergency use and six environmental test panels. These tests include a new respiratory panel that has been developed to rapidly identify and differentiate between respiratory diseases such as COVID-19 and the emerging coronaviruses. The Biomedical Advance Research and Development Initiative, part of the US Department of Defense Strategic Access Program has granted the COVID-19 Panel a grant. The COVID-19 test is based on antigens, and allows clinicians to differentiate symptoms caused by COVID-19 from other respiratory infections. The test has a similar accuracy to the rapid antigen tests that are currently being used. The company is also in the process of developing a test for SARS-CoV-2 for its Respiratory Panel 2.1. This multiplexed nucleic acid amplifying test will be available on the BioFire FilmArray 2.0 and Torch Systems, and will detect SARS-CoV-2 as well as 21 other respiratory pathogens in nasopharyngeal and saliva specimens within less than one hour. The assay is being developed using an accelerated timeframe and submission to the FDA for EUA and 510(k) clearance is anticipated in Q3 of 2020. Although bio-ethanol flame-effect fires are extremely safe to use, they must be kept away from any flammable material like curtains, blankets and pillows. They should not be set close to anything that may catch fire and it is recommended to keep flammable materials at least 10 feet from them. The bioethanol fuel should be stored in a secure, dry location that isn't easily accessible by pets or children. Simple to use A bioethanol fireplace is simple to use and has no flue to be concerned about. All you need is a safe place to put it and some fuel. Once you've filled the burner with fuel, ignite it up. This will produce an appearance of a flame like the real flame. Once the flame has started it will heat the room, but it will emit minimal or no smoke. It also produces lots of heat, much like a wood-burning fire would. They are also simple to maintain and do not require any servicing. A quick wipe down is all they require. In contrast to other tests that are quick that are available, the BioFire RP2.1-EZ test uses an syndromic approach to detect common symptoms of infectious diseases and returns results within 45 minutes. The test is designed for patients with respiratory symptoms that are upper respiratory and has a 98% accuracy rate. The test can identify 19 viruses and 3 bacteria in a single sample which makes it a great option for the treatment of patients. The BioFire platform integrates multiplex testing, sample preparation, and results reporting in one platform. This helps laboratories to streamline their workflow and eliminates the requirement for a sequential process that involves sending out a single tests. This can result in better patient outcomes as the appropriate test is chosen the first time and the need for expensive tests based on culture is eliminated. In addition, the BioFire system can identify pathogens as well as their antimicrobial resistance genes at an molecular level, providing information that is more accurate than conventional methods. Molecular diagnostics is increasingly being used to improve the quality of patient treatment. The BioFire RP2.1 plus panel employs an syndromic method to simultaneously target 23 of the most commonly involved pathogens in respiratory infections. The assay is available on the BioFire film array 2.0 and Torch systems and provides results in just 45 minutes. This assay is available in the US under FDA Emergency Use Authorization. It will be available commercially following the initial DoD requirements are fulfilled. Additionally, biofireplace has developed an automated, sample-to-result assay that allows for the quick identification of COVID-19. This assay is in the process of development and will be made available once the initial DoD demand is fulfilled.